Martin Humphries
LAB

Lab members

Martin Humphries
  • Principal Investigator/Professor of Biochemistry/
    Vice-President & Dean, Faculty of Life Sciences
Martin Humphries Biography
  • Email:
    Martin.Humphries@manchester.ac.uk

  • Research interests:
    Elucidation of the mechanisms responsible for metazoan life; specifically the role of cell adhesion in integrating signalling with tissue environment.
  • Main discoveries:
    Pinpointing sites within extracellular matrix molecules that determine adhesion, developing these agents as anti-inflammatory therapeutics, determining the mechanisms of adhesion receptor activation, and elucidating how adhesion receptors act as sensors of the cell microenvironment.
  • Essential laboratory techniques:
    Hire the best people possible, and do what you can to help them enjoy their research.

  • Top 20 publications | Full publication list | Read more »



Paul Mould
Postdoctoral Research Associate/
Senior Research Scientist
Paul Mould


Janet Askari
Postdoctoral Research Associate
Janet Askari
  • Email:
    janet.a.askari {at} manchester.ac.uk

  • Research interests:
    Integrin structure/function relationships. Prote­omic analysis of integrin adhesion complexes.
  • Essential laboratory equipment:
    An accurate pipette.
  • Education:
    BSc (Hons), Microbiology (University of Kent, UK). PhD, Biochemistry (University of Manchester, UK).

  • Recent Publications


Jon Humphries
Postdoctoral Research Associate
Jon Humphries
  • Email:
    j.d.humphries {at} manchester.ac.uk

  • Research interests:
    Cell adhesion. Proteomic analyses of integrin adhesion complexes. Integrin activation states.
  • Essential laboratory equipment:
    The usual stuff – and long suffering workmates.
  • Key to a happy day in the lab:
    Arriving in the morning, leaving in the evening, lunch in between.
  • Websites:
    Research Profile

  • Recent Publications


Mark Morgan
Postdoctoral Research Associate
Mark Morgan
  • Email:
    mark.r.morgan {at} manchester.ac.uk

  • Research interests:
    Syndecan-mediated control of integrin function.
  • Essential laboratory equipment:
    Cells, bad-ass microscopes and rubber policemen.
  • Key to a happy day in the lab:
    Noise-isolating headphones.
  • Education:
    BSc (Hons), Biomedical Science (University of Sheffield, UK). PhD, Oncology (Cancer Research UK/University of London; GKT School of Medicine); Thesis: Role of the β6 integrin cytoplasmic domain in carcinoma cell invasion.
  • Websites:
    Research Profile

  • Publications


Adam Byron
Postdoctoral Research Associate
Adam Byron
  • Email:
    adam.byron {at} manchester.ac.uk

  • Research interests:
    Proteomic analyses of integrin adhesion com­plexes.
  • Essential laboratory equipment:
    Protein gels; mass spectrometer; (über-fast) computer.
  • Key to a happy day in the lab:
    A clean blot, a noise-free mass spectrum and a high-quality banana.
  • Education:
    BSc (Hons), Biochemistry with Intercalated Year (University of Warwick, UK). PhD, Biochemistry (University of Manchester, UK).
  • Websites:
    Research Profile | Lab Webmaster | Personal Website | Twitter

  • Publications


Angélique Millon-Frémillon
Postdoctoral Research Associate
Angelique Millon-Fremillon
  • Email:
    angelique.millonfremillon {at} manchester.ac.uk

  • Research interests:
    Proteomic analyses of integrin adhesion com­plexes.
  • Essential laboratory techniques:
    Cell biology; microscopy; mass spectrometry; informatic analysis.
  • Education:
    BSc, Cellular Biology and Physiology; MSc, Integrative Cellular Biology; PhD, Cellular Biology (Joseph Fourier University, Grenoble, France). Qualified in animal experimentation.

  • Publications


Sue Craig
Research Technician
Sue Craig
  • Email:
    susan.e.craig {at} manchester.ac.uk

  • Research interests:
    Diverse. Structural over signalling every time!
  • Expertise:
    Cell culture; protein production/purification; finding things!
  • Essential laboratory equipment:
    Sense of humour.
  • Key to a happy day in the lab:
    Iced fingers and reliable dialysis tubing!
  • Education:
    BSc (Hons), Biochemistry (University of Bristol, UK).


Ewa Koper
Research Technician
Ewa Koper
  • Email:
    ewa.koper {at} manchester.ac.uk

  • Research interests:
    Cell adhesion molecules.
  • Essential laboratory equipment:
    A protein column and lots of tubes.
  • Education:
    MSc, Intercollegiate Department of Biotechnology (University of Gdansk and Medical University of Gdansk, Poland). PhD, Neurobiology (Max Planck Institute of Neurobiology, Martinsried, Germany).


Jila Ajeian
Final-Year Postgraduate Student

Cosupervisor: Sue Kimber

Jila Ajeian
  • Email:
    jila.ajeian {at} postgrad.manchester.ac.uk

  • Research interests:
    Proteomic analyses of integrin adhesion com­plexes in human embryonic stem cells.
  • Essential laboratory equipment:
    Well-defined stem cell media; pluripotency markers; mass spectrometer.
  • Key to a happy day in the lab:
    A plate of well-grown, un­differentiated stem cells.
  • Education:
    BSc, Zoology (University of Shahid Beheshti, Tehran, Iran). MSc, Microbiology (University of Tehran, Iran). MRes, Tissue Engineering and Regenerative Medicine (University of Manchester, UK).


Guillaume Jacquemet
Second-Year Postgraduate Student

Funding: Wellcome Trust

Guillaume Jacquemet
  • Email:
    guillaume.jacquemet {at} postgrad.manchester.ac.uk

  • Research interests:
    Cell migration, integrin signalling and small GTPase regulation.
  • Essential laboratory techniques:
    Classical biochemistry and proteomic analyses; microscopy.
  • Key to a happy day in the lab:
    Mycoplasma-free, alive cells.
  • Public engagement:
    Lab Webmaster
  • Education:
    Licence, Biochemistry (University of Reims, France). Master, Interaction cell matrix (University of Reims, France).



Nikki Paul
Second-Year Postgraduate Student

Cosupervisor: Charles Streuli

Funding: CRUK

Nikki Paul
  • Email:
    nikki.paul {at} postgrad.manchester.ac.uk

  • Research interests:
    Proteomic analyses of integrin adhesion com­plexes in mammary epithelial cells.
  • Essential laboratory equipment:
    Microscope; pipette; pre-cast gels!
  • Key to a happy day in the lab:
    Caffeine and sucrose.
  • Education:
    BSc (Hons), Biochemistry with a Year in Industry (University of York, UK).


Joe Robertson
Second-Year Postgraduate Student

Funding: BBSRC

Joe Robertson
  • Email:
    joseph.robertson {at} postgrad.manchester.ac.uk

  • Research interests:
    Phosphoproteomic analyses of integrin adhesion complexes.
  • Essential laboratory equipment:
    Mass spectrometer.
  • Key to a happy day in the lab:
    A vending machine well-stocked with purple Yorkies.
  • Education:
    BSc (Hons), Medical Microbiology and Immunology (Newcastle University, UK).


Daniel Ng
First-Year Postgraduate Student

Funding: Wellcome Trust

Dan Ng
  • Email:
    daniel.ng {at} postgrad.manchester.ac.uk

  • Research interests:
    Focal adhesion disassembly dynamics.
  • Essential laboratory equipment:
    Patient post-docs.
  • Key to a happy day in the lab:
    Breakfast.
  • Education:
    BSc (Hons), Medical Biochemistry (University of Mancester, UK).





Previous lab members



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Close collaborators



Rachel Lennon
Wellcome Trust Intermediate Clinical Fellow/
Honorary Consultant in Paediatric Nephrology
Rachel Lennon
  • Email:
    rachel.lennon {at} manchester.ac.uk

  • Research interests:
    Understanding mechanisms of proteinuria, focussing on glomerular podocyte adhesion in health and disease.
  • Essential laboratory equipment:
    Lab book.
  • Key to a happy day in the lab:
    Focus.
  • Education:
    BMedSci, BMBS (University of Nottingham, UK). PhD (University of Bristol, UK). MRCP, Paediatrics. CCT, Paedia­trics/Paediatric Nephrology.
  • Websites:
    Research Profile